GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs11733284 | 1 | rs6832503 | chr4:48028442 | NIPAL1 | chr4:48018791-48039078:+ | -0.29 | -9.76 | 1.21E-20 | Renal underexcretion gout;Gout |
| THCA | cis | rs6832769 | 1 | rs6832769 | chr4:56298194 | TMEM165 | chr4:56262090-56292342:+ | -0.15 | -3.86 | 0.00013 | Personality dimensions |
| THCA | cis | rs17407555 | 1 | rs6833988 | chr4:10295586 | SLC2A9 | chr4:9827850-10041872:- | 0.19 | 3.37 | 0.000803 | Schizophrenia (age at onset) |
| THCA | cis | rs6832769 | 1 | rs6834676 | chr4:56298414 | TMEM165 | chr4:56262090-56292342:+ | -0.14 | -3.61 | 0.000335 | Personality dimensions |
| THCA | cis | rs10518128 | 1 | rs6834806 | chr4:75715826 | BTC | chr4:75671448-75719882:- | 0.2 | 3.95 | 8.9E-5 | Electroencephalogram traits |
| THCA | cis | rs2412488 | 1 | rs6834934 | chr4:54242085 | SCFD2 | chr4:53739152-54232242:- | 0.2 | 3.76 | 0.000189 | DNA methylation (variation) |
| THCA | cis | rs7692995 | 1 | rs6835186 | chr4:17984316 | DCAF16 | chr4:17802280-17812381:- | -0.2 | -4.39 | 1.41E-5 | Height |
| THCA | cis | rs7438704 | 1 | rs6837335 | chr4:48363983 | OCIAD1 | chr4:48833015-48863831:+ | 0.14 | 4.18 | 3.45E-5 | Crohn's disease;Inflammatory bowel disease |
| THCA | cis | rs1949733 | 1 | rs6837429 | chr4:8502374 | C4orf23 | chr4:8440604-8495258:+ | -0.35 | -7.42 | 5.46E-13 | Response to antineoplastic agents |
| THCA | cis | rs6832769 | 1 | rs6837710 | chr4:56374455 | TMEM165 | chr4:56262090-56292342:+ | -0.14 | -3.55 | 0.000426 | Personality dimensions |
| THCA | cis | rs7665090 | 1 | rs6839064 | chr4:103555676 | CISD2 | chr4:103790135-103809913:+ | -0.16 | -3.62 | 0.000321 | Primary biliary cirrhosis |
| THCA | cis | rs7665090 | 1 | rs6839064 | chr4:103555676 | NFKB1 | chr4:103422486-103538458:+ | 0.15 | 4.2 | 3.16E-5 | Primary biliary cirrhosis |
| THCA | cis | rs599083 | 1 | rs683978 | chr11:68192421 | LOC645332 | chr11:67559240-67572807:- | 0.16 | 3.5 | 0.000514 | Bone mineral density (spine) |
| THCA | cis | rs7692995 | 1 | rs6839954 | chr4:17984129 | DCAF16 | chr4:17802280-17812381:- | -0.19 | -4.34 | 1.73E-5 | Height |
| THCA | cis | rs7692995 | 1 | rs6840334 | chr4:17984277 | DCAF16 | chr4:17802280-17812381:- | -0.2 | -4.39 | 1.41E-5 | Height |